Publications
Our lab is dedicated to the study of blood stem cell formation in development and disease. Our published work is a testament to our commitment to advancing our understanding of these areas. We encourage you to explore our research manuscripts.
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We support open science and always deposit our work on bioRxiv prior to peer review.
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2024
Mahony CB, Monteiro R. Protocol for the analysis of hematopoietic lineages in the whole kidney marrow of adult zebrafish. STAR Protoc. 2024 Jan 22;5(1):102810. doi: 10.1016/j.xpro.2023.102810. [Epub ahead of print] PubMed PMID: 38261517; PubMed Central PMCID: PMC10835462.
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2023
Mahony CB, Copper L, Vrljicak P, Noyvert B, Constantinidou C, Browne S, Pan Y, Palles C, Ott S, Higgs MR, Monteiro R. Lineage skewing and genome instability underlie marrow failure in a zebrafish model of GATA2 deficiency. Cell Rep. 2023 Jun 27;42(6):112571. doi: 10.1016/j.celrep.2023.112571. Epub 2023 May 31. PubMed PMID: 37256751.
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2022
Panara V, Monteiro R, Koltowska K. Epigenetic Regulation of Endothelial Cell Lineages During Zebrafish Development-New Insights From Technical Advances. Front Cell Dev Biol. 2022;10:891538. doi: 10.3389/fcell.2022.891538. eCollection 2022. Review. PubMed PMID: 35615697; PubMed Central PMCID: PMC9125237.
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Thambyrajah R, Monteiro R. In the spotlight: the role of TGFβ signalling in haematopoietic stem and progenitor cell emergence. Biochem Soc Trans. 2022 Apr 29;50(2):703-712. doi: 10.1042/BST20210363. Review. PubMed PMID: 35285494; PubMed Central PMCID: PMC9162451.
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2021
Mahony CB, Cacialli P, Pasche C, Monteiro R, Savvides SN, Bertrand JY. Hapln1b, a central organizer of the ECM, modulates kit signaling to control developmental hematopoiesis in zebrafish. Blood Adv. 2021 Dec 14;5(23):4935-4948. doi: 10.1182/bloodadvances.2020001524. PubMed PMID: 34543380; PubMed Central PMCID: PMC9152995.
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Gioacchino E, Koyunlar C, Zink J, de Looper H, de Jong M, Dobrzycki T, Mahony CB, Hoogenboezem R, Bosch D, van Strien PMH, van Royen ME, French PJ, Bindels E, Gussinklo KJ, Monteiro R, Touw IP, de Pater E. Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish. Blood Adv. 2021 Jul 13;5(13):2687-2700. doi: 10.1182/bloodadvances.2020002993. PubMed PMID: 34170285; PubMed Central PMCID: PMC8288679.
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2020
Dobrzycki T, Mahony CB, Krecsmarik M, Koyunlar C, Rispoli R, Peulen-Zink J, Gussinklo K, Fedlaoui B, de Pater E, Patient R, Monteiro R. Deletion of a conserved Gata2 enhancer impairs haemogenic endothelium programming and adult Zebrafish haematopoiesis. Commun Biol. 2020 Feb 13;3(1):71. doi: 10.1038/s42003-020-0798-3. PubMed PMID: 32054973; PubMed Central PMCID: PMC7018942.
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Dobrzycki T, Krecsmarik M, Monteiro R. Genotyping and Quantification of In Situ Hybridization Staining in Zebrafish. J Vis Exp. 2020 Jan 28;(155). doi: 10.3791/59956. PubMed PMID: 32065138.
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Dobrzycki T, Lalwani M, Telfer C, Monteiro R, Patient R. The roles and controls of GATA factors in blood and cardiac development. IUBMB Life. 2020 Jan;72(1):39-44. doi: 10.1002/iub.2178. Epub 2019 Nov 28. Review. PubMed PMID: 31778014; PubMed Central PMCID: PMC6973044.
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2019
Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R. Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Nat Commun. 2019 Aug 8;10(1):3577. doi: 10.1038/s41467-019-11423-2. PubMed PMID: 31395869; PubMed Central PMCID: PMC6687740.
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2018
Dobrzycki T, Krecsmarik M, Bonkhofer F, Patient R, Monteiro R. An optimised pipeline for parallel image-based quantification of gene expression and genotyping after in situ hybridisation. Biol Open. 2018 Apr 9;7(4). doi: 10.1242/bio.031096. PubMed PMID: 29535102; PubMed Central PMCID: PMC5936060.
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Full bibliography here.